Hi
We have the following setup :
1. Installation is on VM Machines;
2. Repository is on the Database Server, the physical database is mapped to C Drive, Repository mapped to D drive, and pagesys file on E drive. All drives are mapped to different physical drives in the VM cluster
3. Size for C and D drives is 50gb, E is 20gb
4. Enforced restriction on file attachment size to 3Mb in Site Configuration. Anything over that is stored in sharepoint and a reference link attached. This avoids 800Mb movies being attached to a defect.
We have nearly a 100 QC Projects defined and largest repository is about 3gb.
Hope this helps